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Todd Gurley matched a season high with 97 yards rushing and scored a touchdown, Malcolm Brown added a score, and the Los Angeles Rams returned home to earn a 17-7 victory Sunday in a defensive tussle against the Chicago Bears.

San Francisco quarterback Jimmy Garoppolo passed for a career-high 424 yards and tied a career high with four touchdowns, including the game-winning 25-yard score to Jeff Wilson Jr. with 31 seconds remaining, as the host 49ers rallied past the Arizona Cardinals 36-26 Sunday in Santa Clara, Calif.

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Jonathan Williams rushed for 116 yards, and Marlon Mack ran for 109 yards and a touchdown Sunday as the Indianapolis Colts stopped the visiting Jacksonville Jaguars 33-13, moving into a first-place tie in the AFC South with Houston.